Publications | The Noble Lab

PUBLICATIONS

78.

A Catalyst-Free Approach for N-Formylation of Amines with Aldehydes via Aerobic Oxidation

Qingwei Guo, Aazath Kathar, Jordan Barker and Adam Noble*

Org. Biomol. Chem. 2026, 24 , 5994–5998

A Catalyst-Free Approach for N-Formylation of Amines with Aldehydes via Aerobic Oxidation

77.

Ketones to Ketyls by Radical Relocation (News & Views)

Adam Noble*

Nat. Chem. 2026, DOI: 10.1038/s41557-026-02181-y

Ketones to Ketyls by Radical Relocation (News & Views)

76.

Aldehyde–Olefin Couplings by Photoinduced Reduction of Electron-Deficient Olefins with Hantzsch Ester Anions

Zhihang Li and Adam Noble*

Angew. Chem. Int. Ed. 2026, 65, e9744019

Aldehyde–Olefin Couplings by Photoinduced Reduction of Electron-Deficient Olefins with Hantzsch Ester Anions

75.

Iron-Photocatalyzed C(sp³)–H Phosphonylation of Alkanes

Ya Dong, Wangyujing Han, Hanwen Zhang, Santosh K. Pagire, Harry Meats,

Adam Noble* and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2026, 65, e6650940

Iron-Photocatalyzed C(sp³)–H Phosphonylation of Alkanes

74.

Boron-Mediated Hydroalkylation of Unactivated Olefins:
An Anti-Markovnikov Approach to Congested Carbon Centers

Hanwen Zhang, Ruocheng Sang, Gianluca Simionato, Jasper L. Tyler,

Adam Noble* and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2026, 148, 12227–12234

Boron-Mediated Hydroalkylation of Unactivated Olefins:
An Anti-Markovnikov Approach to Congested Carbon Centers

73.

Breaking the ‘Rule-of-Five’ to Access Bridged Bicyclic Heteroaromatic Bioisosteres

Ze-Xin Zhang, KaiChen Shu, Michael J. Tilby, Mark John P. Mandigma, Yiheng Guo, Jasper L. Tyler, Adam Noble* and Varinder K. Aggarwal*

Nat. Synth. 2026, 5, 790–797

Breaking the ‘Rule-of-Five’ to Access Bridged Bicyclic Heteroaromatic Bioisosteres

72.

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues

Malcolm R. P. George, Lobna A. Elsadek, Max Deering, Larissa Costa de Almeida, Jasper L. Tyler, Adam Noble, Valerie J. Paul, Hendrik Luesch,

Craig P. Butts* and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2026, 65, e23117

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues

71.

Synthesis of Indoloazepinone Scaffolds Using Sequential Photochemical and Photocatalytic Reactions

Kate A. Ellis-Sawyer, Tomos Alderman, Kevin I. Booker-Milburn,

Varinder K. Aggarwal* and Adam Noble*

Org. Lett. 2025, 27, 9727–9731

Synthesis of Indoloazepinone Scaffolds Using Sequential Photochemical and Photocatalytic Reactions

70.

Intramolecular Lithiation-Borylation for the Stereoselective Synthesis of Cyclopentyl and Cyclobutyl Bis-Boronic Esters

Christopher J. Cope, Margherita Zanini, Malcolm R. P. George, Daniel Otero, Jana Sendra, Adam Noble, Julien Lefranc, Raphaël Robiette and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2025, 64, e202512896

Intramolecular Lithiation-Borylation for the Stereoselective Synthesis of Cyclopentyl and Cyclobutyl Bis-Boronic Esters

69.

Total Synthesis and Structure Determination of Mycapolyol E Using Iterative Homologation of Boronic Esters

Sheenagh G. Aiken, Dylan Rigby, Daniele Fiorito, Malcolm R. P. George,

Simon Wübbolt, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Novit 2025, 1, e70003

Total Synthesis and Structure Determination of Mycapolyol E Using Iterative Homologation of Boronic Esters

68.

Boron-Mediated Modular Assembly of Tetrasubstituted Alkenes

Liang Wei, Mihai V. Popescu, Adam Noble, Robert S. Paton*

and Varinder K. Aggarwal*

Nature 2025, 634, 975–982

Boron-Mediated Modular Assembly of Tetrasubstituted Alkenes

67.

Recent Advances in Photoinduced Ketyl and Ketyl-Type Radical Generation from Aldehyde Derivatives (invited review)

Zhihang Li, Harry Meats, Tomos Alderman and Adam Noble*

Synthesis 2025, 57, 3543–3553

[Invited contribution for special topic dedicated to Thieme Chemistry Journal Awardees 2025]

Recent Advances in Photoinduced Ketyl and Ketyl-Type Radical Generation from Aldehyde Derivatives (invited review)

66.

Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for Debrominative Borylations

Jingjing Wu, Hui Wang, Huaquan Fang, Kevin C. Wang, Deborin Ghosh, Valerio Fasano, Adam Noble* and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2025, 147, 19450–19457

[Highlighted in OPRD]

Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for Debrominative Borylations

65.

The Combination of Synthesis and Ultra-High-Resolution NMR Spectroscopy Reveals the Correct Structure of Caylobolide A

Malcolm R. P. George, Max Deering, Daniele Fiorito, Keren Solomon, Kevin Tidgewell, Adam Noble, Craig P. Butts* and Varinder K. Aggarwal*

Nat. Synth. 2025, 4, 859–868

The Combination of Synthesis and Ultra-High-Resolution NMR Spectroscopy Reveals the Correct Structure of Caylobolide A

64.

From Geranium Lakes to Catalysis with Light

Adam Noble*

Nat. Chem. 2024, 16, 1734

From Geranium Lakes to Catalysis with Light

63.

Aldehyde–Olefin Couplings Via Sulfoxylate-Mediated Oxidative Generation of Ketyl Radical Anions

Zhihang Li, Joseph A. Tate and Adam Noble*

J. Am. Chem. Soc. 2024, 146, 26616–26621

[Highlighted in OPRD, Synfacts, Synthesis Spotlight]

Aldehyde–Olefin Couplings Via Sulfoxylate-Mediated Oxidative Generation of Ketyl Radical Anions

62.

Platinum-Catalyzed Regio- and Enantioselective Diboration of Unactivated Alkenes with (pin)B−B(dan)

Huaquan Fang, Niket Manoj, Mihai V. Popescu, Adam Noble,

Robert S. Paton* and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2024, 63, e202413504

Platinum-Catalyzed Regio- and Enantioselective Diboration of Unactivated Alkenes with (pin)B−B(dan)

61.

Synthesis of 1-Azabicyclo[2.1.1]hexanes via Formal Single Electron Reduction of Azabicyclo[1.1.0]butanes Under Photochemical Conditions

Margherita Zanini, Adam Noble* and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2024, 63, e202410207

Synthesis of 1-Azabicyclo[2.1.1]hexanes via Formal Single Electron Reduction of Azabicyclo[1.1.0]butanes Under Photochemical Conditions

60.

Simultaneous Stereoinvertive and Stereoselective C(sp³)–C(sp³) Cross-Coupling of Boronic Esters and Allylic Carbonates

Hong-Cheng Shen, Ze-Shu Wang, Adam Noble and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2024, 146, 13719–13726

Simultaneous Stereoinvertive and Stereoselective C(sp³)–C(sp³) Cross-Coupling of Boronic Esters and Allylic Carbonates

59.

Stereospecific Conversion of Boronic Esters into Enones using Methoxyallene: Application in the Total Synthesis of 10-Deoxymethynolide

Kristian J. Chambers, Patthadon Sanghong, Daniel Carter Martos, Giorgia Casoni, Rory C. Mykura, Durga Prasad Hari, Adam Noble

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2023, 62, e202312054

Stereospecific Conversion of Boronic Esters into Enones using Methoxyallene: Application in the Total Synthesis of 10-Deoxymethynolide

58.

Convergent Deboronative and Decarboxylative Phosphonylation Enabled by the Phosphite Radical Trap “BecaP”

Santosh K. Pagire, Chao Shu, Dominik Reich, Adam Noble*

and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2023, 145, 18649–18657

Convergent Deboronative and Decarboxylative Phosphonylation Enabled by the Phosphite Radical Trap “BecaP”

57.

Photoredox-Catalyzed Decarboxylative Bromination, Chlorination and Thiocyanation Using Inorganic Salts

Jingjing Wu, Chao Shu, Zhihang Li, Adam Noble*

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2023, 62, e202309684

Photoredox-Catalyzed Decarboxylative Bromination, Chlorination and Thiocyanation Using Inorganic Salts

56.

Iridium-Catalyzed Asymmetric Difunctionalization of C–C σ-Bonds Enabled by Ring-Strained Boronate Complexes

Hong-Cheng Shen, Mihai V. Popescu, Ze-Shu Wang, Louis de Lescure,

Adam Noble, Robert S. Paton* and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2023, 145, 16508–16516

Iridium-Catalyzed Asymmetric Difunctionalization of C–C σ-Bonds Enabled by Ring-Strained Boronate Complexes

55.

Copper-Mediated Dehydrogenative C(sp³)–H Borylation of Alkanes

Ruocheng Sang, Wangyujing Han, Hanwen Zhang, Carla M. Saunders,

Adam Noble* and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2023, 145, 15207–15217

Copper-Mediated Dehydrogenative C(sp³)–H Borylation of Alkanes

54.

Synthesis of Dihydropyridine Spirocycles by Semi-Pinacol-Driven Dearomatization of Pyridines

Joseph Abell, Christian Bold, Laia Vicens, Tom Jentsch, Noelia Velasco, Jasper L. Tyler, Robert N. Straker, Adam Noble and Varinder K. Aggarwal*

Org. Lett. 2023, 25, 400–404

Synthesis of Dihydropyridine Spirocycles by Semi-Pinacol-Driven Dearomatization of Pyridines

53.

Strain-Release Driven Epoxidation and Aziridination of Bicyclo[1.1.0]butanes via Palladium Catalyzed σ-Bond Nucleopalladation

Bernhard Wölfl, Nils Winter, Jiajing Li, Adam Noble

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2023, 62, e202217064

Strain-Release Driven Epoxidation and Aziridination of Bicyclo[1.1.0]butanes via Palladium Catalyzed σ-Bond Nucleopalladation

52.

Iterative Synthesis of 1,3-Polyboronic Esters with High Stereocontrol and Application to the Synthesis of Bahamaolide A

Sheenagh G. Aiken, Joseph M. Bateman, Hsuan-Hung Liao, Alexander Fawcett, Teerawut Bootwicha, Paolo Vincetti, Eddie L. Myers,

Adam Noble and Varinder K. Aggarwal*

Nat. Chem. 2023, 15, 248–256

Iterative Synthesis of 1,3-Polyboronic Esters with High Stereocontrol and Application to the Synthesis of Bahamaolide A

51.

Automated Stereocontrolled Assembly-Line Synthesis of Organic Molecules

Valerio Fasano, Rory C. Mykura, James M. Fordham, Jack J. Rogers, Borys Banecki, Adam Noble and Varinder K. Aggarwal*

Nat. Synth. 2022, 1, 902–907

Automated Stereocontrolled Assembly-Line Synthesis of Organic Molecules

50.

Four-Component Strain-Release-Driven Synthesis of Functionalized Azetidines

Jasper L. Tyler, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2022, 61, e202214049

Four-Component Strain-Release-Driven Synthesis of Functionalized Azetidines

49.

Facile Conversion of α-Amino Acids into α-Amino Phosphonates by Decarboxylative Phosphorylation using Visible-Light Photocatalysis

Dominik Reich, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2022, 61, e202207063

Facile Conversion of α-Amino Acids into α-Amino Phosphonates by Decarboxylative Phosphorylation using Visible-Light Photocatalysis

48.

Dual Nickel/Photoredox-Catalyzed Site-Selective Cross-Coupling of
1,2-Bis-Boronic Esters Enabled by 1,2-Boron Shifts

Hui Wang, Wangyujing Han, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2022, 61, e202207988

Dual Nickel/Photoredox-Catalyzed Site-Selective Cross-Coupling of
1,2-Bis-Boronic Esters Enabled by 1,2-Boron Shifts

47.

Diastereodivergent Synthesis of Cyclopentyl Boronic Esters Bearing Contiguous Fully Substituted Stereocenters

Molly E. Fairchild, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2022, 61, e202205816

Diastereodivergent Synthesis of Cyclopentyl Boronic Esters Bearing Contiguous Fully Substituted Stereocenters

46.

Stereocontrolled Total Synthesis of Bastimolide B Using Iterative Homologation of Boronic Esters

Daniele Fiorito, Selbi Keskin, Joseph M. Bateman, Malcolm George,

Adam Noble and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2022, 144, 7995–8001

Stereocontrolled Total Synthesis of Bastimolide B Using Iterative Homologation of Boronic Esters

45.

Selective Coupling of 1,2-Bis-Boronic Esters at the more Substituted Site through Visible-Light Activation of Electron Donor-Acceptor Complexes

Hui Wang, Jingjing Wu, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2022, 61, e202202061

Selective Coupling of 1,2-Bis-Boronic Esters at the more Substituted Site through Visible-Light Activation of Electron Donor-Acceptor Complexes

44.

Sequential Photocatalytic Reactions for the Diastereoselective Synthesis of Cyclobutane Scaffolds

Mark J. Deeprose, Martin Lowe, Adam Noble*, Kevin I. Booker-Milburn*

and Varinder K. Aggarwal*

Org. Lett. 2022, 24, 137–141

Sequential Photocatalytic Reactions for the Diastereoselective Synthesis of Cyclobutane Scaffolds

43.

Strain-Release-Driven Friedel-Crafts Spirocyclization of Azabicyclo[1.1.0]butanes

Jasper L. Tyler, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2022, 61, e202114235

Strain-Release-Driven Friedel-Crafts Spirocyclization of Azabicyclo[1.1.0]butanes

42.

Direct Observation of Reactive Intermediates by Time-Resolved Spectroscopy Unravels the Mechanism of a Radical-Induced 1,2-Metalate Rearrangement

Luke Lewis-Borrell, Mahima Sneha, Ian P. Clark, Valerio Fasano,

Adam Noble, Varinder K. Aggarwal* and Andrew J. Orr-Ewing*

J. Am. Chem. Soc. 2021, 143, 17191–17199

Direct Observation of Reactive Intermediates by Time-Resolved Spectroscopy Unravels the Mechanism of a Radical-Induced 1,2-Metalate Rearrangement

41.

Chiral Benzothiophene Synthesis via Enantiospecific Coupling of Benzothiophene S-Oxides with Boronic Esters

Ruocheng Sang, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2021, 60, 25313–25317

Chiral Benzothiophene Synthesis via Enantiospecific Coupling of Benzothiophene S-Oxides with Boronic Esters

40.

Diastereoselective Photoredox-Catalyzed [3 + 2] Cycloadditions of
N-Sulfonyl Cyclopropylamines with Electron-Deficient Olefins

Dawn H. White, Adam Noble, Kevin I. Booker-Milburn*

and Varinder K. Aggarwal*

Org. Lett. 2021, 23, 3038–3042

Diastereoselective Photoredox-Catalyzed [3 + 2] Cycloadditions of
N-Sulfonyl Cyclopropylamines with Electron-Deficient Olefins

39.

Strain-Release Driven Spirocyclization of Azabicyclo[1.1.0]butyl
Ketones

Jasper L. Tyler, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2021, 60, 11824–11829

Strain-Release Driven Spirocyclization of Azabicyclo[1.1.0]butyl
Ketones

38.

Divergent, Strain-Release Reactions of Azabicyclo[1.1.0]butyl Carbinols: Semipinacol or Spiroepoxy Azetidine Formation

Charlotte H. U. Gregson, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2021, 60, 7360–7365

Divergent, Strain-Release Reactions of Azabicyclo[1.1.0]butyl Carbinols: Semipinacol or Spiroepoxy Azetidine Formation

37.

Metal-Free Photoinduced C(sp³)–H Borylation of Alkanes

Chao Shu, Adam Noble* and Varinder K. Aggarwal*

Nature 2020, 586, 714–719

Metal-Free Photoinduced C(sp³)–H Borylation of Alkanes

36.

α-Selective Ring Opening Reactions of Bicyclo[1.1.0]butyl Boronic Ester with Nucleophiles

Lin Guo, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2021, 60, 212–216

α-Selective Ring Opening Reactions of Bicyclo[1.1.0]butyl Boronic Ester with Nucleophiles

35.

Photoinduced Fragmentation Borylation of Cyclic Alcohols and Hemiacetals

Chao Shu, Rudrakshula Madhavachary, Adam Noble*

and Varinder K. Aggarwal*

Org. Lett. 2020, 22, 7213–7218

Photoinduced Fragmentation Borylation of Cyclic Alcohols and Hemiacetals

34.

Iridium-Catalyzed Enantioselective Synthesis of Chiral Bicyclo[1.1.1]pentanes by 1,3-Difunctionalization of [1.1.1]Propellane

Songjie Yu, Changcheng Jing, Adam Noble and Varinder K. Aggarwal*

Org. Lett. 2020, 22, 5650–5655

Iridium-Catalyzed Enantioselective Synthesis of Chiral Bicyclo[1.1.1]pentanes by 1,3-Difunctionalization of [1.1.1]Propellane

33.

Stereospecific 1,2-Migrations of Boronate Complexes Induced by Electrophiles (review)

Hui Wang, Changcheng Jing, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2020, 59, 16859–16872

Stereospecific 1,2-Migrations of Boronate Complexes Induced by Electrophiles (review)

32.

Divergent, Stereospecific Mono- and Difluoromethylation of Boronic Esters

Valerio Fasano, Nils Winter, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2020, 59, 8502–8506

Divergent, Stereospecific Mono- and Difluoromethylation of Boronic Esters

31.

Visible Light-Driven Strain-Increase Ring Contraction Allows the Synthesis of Cyclobutyl Boronic Esters

Raffael Davenport, Mattia Silvi, Adam Noble, Zied Hosni, Natalie Fey

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2020, 59, 6525–6528

Visible Light-Driven Strain-Increase Ring Contraction Allows the Synthesis of Cyclobutyl Boronic Esters

30.

Decarboxylative Conjunctive Cross-coupling of Vinyl Boronic Esters using Metallaphotoredox Catalysis

Riccardo S. Mega, Vincent K. Duong, Adam Noble*

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2020, 59, 4375–4379

Decarboxylative Conjunctive Cross-coupling of Vinyl Boronic Esters using Metallaphotoredox Catalysis

29.

1,3-Difunctionalizations of [1.1.1]Propellane via 1,2-Metallate Rearrangements of Boronate Complexes

Songjie Yu, Changcheng Jing, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2020, 59, 3917–3921

1,3-Difunctionalizations of [1.1.1]Propellane via 1,2-Metallate Rearrangements of Boronate Complexes

28.

Ring-Opening Lithiation–Borylation of 2-Trifluoromethyl Oxirane: A Route to Versatile Tertiary Trifluoromethyl Boronic Esters

Meganathan Nandakumar, Belén Rubial, Adam Noble,

Eddie L. Myers* and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2020, 59, 1187–1191

Ring-Opening Lithiation–Borylation of 2-Trifluoromethyl Oxirane: A Route to Versatile Tertiary Trifluoromethyl Boronic Esters

27.

Methylenespiro[2.3]hexanes via Nickel-Catalyzed Cyclopropanations with [1.1.1]Propellane

Songjie Yu, Adam Noble, Robin B. Bedford* and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2019, 141, 20325–20334

Methylenespiro[2.3]hexanes via Nickel-Catalyzed Cyclopropanations with [1.1.1]Propellane

26.

Photoinduced Deoxygenative Borylations of Aliphatic Alcohols

Jingjing Wu, Robin Bär, Lin Guo, Adam Noble

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2019, 58, 18830–18834

Photoinduced Deoxygenative Borylations of Aliphatic Alcohols

25.

1,2-Boron Shifts of β-Boryl Radicals Generated from Bis-boronic Esters Using Photoredox Catalysis

Daniel Kaiser, Adam Noble, Valerio Fasano and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2019, 141, 14104–14109

1,2-Boron Shifts of β-Boryl Radicals Generated from Bis-boronic Esters Using Photoredox Catalysis

24.

Triphenylphosphine and Sodium Iodide: A New Catalyst Combination to Rival Precious Metal Complexes in Visible Light Photoredox Catalysis (highlight)

Adam Noble and Varinder K. Aggarwal*

Sci. China Chem. 2019, 62, 1083–1084

Triphenylphosphine and Sodium Iodide: A New Catalyst Combination to Rival Precious Metal Complexes in Visible Light Photoredox Catalysis (highlight)

23.

Catalyst-Free Deaminative Functionalizations of Primary Amines via Photoinduced Single-Electron Transfer

Jingjing Wu, Phillip S. Grant, Xiabing Li, Adam Noble

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2019, 58, 5697–5701

Catalyst-Free Deaminative Functionalizations of Primary Amines via Photoinduced Single-Electron Transfer

22.

Photoredox-Catalyzed Cyclobutane Synthesis via a Deboronative Radical Addition–Polar Cyclization Cascade

Chao Shu, Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2019, 58, 1366–1370

Photoredox-Catalyzed Cyclobutane Synthesis via a Deboronative Radical Addition–Polar Cyclization Cascade

21.

Enantiospecific Synthesis of ortho-Substituted 1,1-Diarylalkanes by a 1,2-Metalate Rearrangement/anti-S 2' Elimination/Rearomatizing Allylic Suzuki-Miyaura Reaction Sequence

Belén Rubial, Beatrice S. L. Collins, Raphael Bigler, Stefan Aichhorn,

Adam Noble and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2019, 58, 1366–1370

Enantiospecific Synthesis of ortho-Substituted 1,1-Diarylalkanes by a 1,2-Metalate Rearrangement/anti-S 2' Elimination/Rearomatizing Allylic Suzuki-Miyaura Reaction Sequence

20.

Complex Boron-Containing Molecules through a 1,2-Metalate Rearrangement/anti-S 2' Elimination/Cycloaddition Reaction Sequence

Chloe Tillin, Raphael Bigler, Renata Calo-Lapido, Beatrice S. L. Collins,

Adam Noble and Varinder K. Aggarwal*

Synlett 2019, 30, 449–453

Complex Boron-Containing Molecules through a 1,2-Metalate Rearrangement/anti-S 2' Elimination/Cycloaddition Reaction Sequence

19.

Chiral Aniline Synthesis via Stereospecific C(sp³)–C(sp²) Coupling of Boronic Esters with Aryl Hydrazines

Venkataraman Ganesh, Adam Noble and Varinder K. Aggarwal*

Org. Lett. 2018, 20, 6144–6147

Chiral Aniline Synthesis via Stereospecific C(sp³)–C(sp²) Coupling of Boronic Esters with Aryl Hydrazines

18.

Synthesis of Functionalized Cyclopropanes from Carboxylic Acids via a Radical Addition–Polar Cyclization Cascade

Chao Shu, Riccardo S. Mega, Björn J. Andreassen, Adam Noble*

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2018, 57, 15430–15434

Synthesis of Functionalized Cyclopropanes from Carboxylic Acids via a Radical Addition–Polar Cyclization Cascade

17.

Photoinduced Deaminative Borylation of Alkylamines

Jingjing Wu, Lin He, Adam Noble and Varinder K. Aggarwal*

J. Am. Chem. Soc. 2018, 140, 10700–10704

Photoinduced Deaminative Borylation of Alkylamines

16.

Enantiodivergent Synthesis of Allenes by Point to Axial Chirality Transfer

Roly J. Armstrong, Meganathan Nandakumar, Rafael M. P. Dias,

Adam Noble, Eddie L. Myers and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2018, 57, 8203–8208

Enantiodivergent Synthesis of Allenes by Point to Axial Chirality Transfer

15.

Stereo- and Regiocontrolled Methylboration of Terminal Alkynes

Oleksandr Zhurakovskyi, Rafael M. P. Dias, Adam Noble

and Varinder K. Aggarwal*

Org. Lett. 2018, 20, 3136–3139

Stereo- and Regiocontrolled Methylboration of Terminal Alkynes

14.

Enantiospecific Three-Component Alkylation of Furan and Indole

Mattia Silvi, Raffael Schrof, Adam Noble and Varinder K. Aggarwal*

Chem. Eur. J. 2018, 24, 4279–4282

Enantiospecific Three-Component Alkylation of Furan and Indole

13.

Enantiospecific sp²–sp³ Coupling of o- and p-Phenols with Secondary and Tertiary Boronic Esters

Claire M. Wilson, Venkataraman Ganesh, Adam Noble

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2017, 56, 16318–16322

Enantiospecific sp²–sp³ Coupling of o- and p-Phenols with Secondary and Tertiary Boronic Esters

Postdoc, PhD, and Undergraduate

Visible-Light-Mediated Decarboxylative Radical Additions to Vinyl Boronic Esters: Rapid Access to γ-Amino Boronic Esters

Adam Noble, Riccardo S. Mega, Daniel Pflästerer, Eddie L. Myers

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2018, 57, 2155–2159

12.

Visible-Light-Mediated Decarboxylative Radical Additions to Vinyl Boronic Esters: Rapid Access to γ-Amino Boronic Esters

Enantiospecific Trifluoromethyl-Radical-Induced Three-Component Coupling of Boronic Esters with Furans

Yahui Wang, Adam Noble, Christopher Sandford

and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2017, 56, 1810–1814

11.

Enantiospecific Trifluoromethyl-Radical-Induced Three-Component Coupling of Boronic Esters with Furans

Short, Enantioselective Total Synthesis of Tatanan A

Through an Assembly-Line Synthesis Approach

Adam Noble, Stefan Roesner and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2016, 55, 15920–15924

10.

Short, Enantioselective Total Synthesis of Tatanan A Through an Assembly-Line Synthesis Approach

Enantiospecific Alkynylation of Alkylboronic Esters

Yahui Wang, Adam Noble, Eddie L. Myers and Varinder K. Aggarwal*

Angew. Chem. Int. Ed. 2016, 55, 4270–4274

Enantiospecific Alkynylation of Alkylboronic Esters

Palladium-Catalyzed Reactions of Allylic Boronic Esters with Nucleophiles: Novel Umpolung Reactivity

Phillip J. Unsworth, Lonrenz E. Löffler, Adam Noble and Varinder K. Aggarwal*

Synlett 2015, 26, 1567–1572

Palladium-Catalyzed Reactions of Allylic Boronic Esters with Nucleophiles: Novel Umpolung Reactivity

Merging Photoredox and Nickel Catalysis: Decarboxylative

Cross-Coupling of Carboxylic Acids with Vinyl Halides

Adam Noble, Stefan J. McCarver and David W. C. MacMillan*

J. Am. Chem. Soc. 2015, 137, 624–627

Merging Photoredox and Nickel Catalysis: Decarboxylative Cross-Coupling of Carboxylic Acids with Vinyl Halides

Photoredox α-Vinylation of α-Amino Acids and N-Aryl Amines

Adam Noble and David W. C. MacMillan*

J. Am. Chem. Soc. 2014, 136, 11602–11605

Photoredox α-Vinylation of α-Amino Acids and N-Aryl Amines

Nitro-Mannich Reaction (review)

Adam Noble and James C. Anderson*

Chem. Rev. 2013, 113, 2887–2939

images_medium_cr-2012-00272t_0163_edited

An Intramolecular Nitro-Mannich Route to Functionalised Tetrahydroquinolines

James. C. Anderson*, Adam Noble, and Pascual Ribelles Torres

Tetrahedron Lett. 2012, 53, 5707–5710

Reductive Nitro-Mannich Route for the Synthesis of 1,2-Diamine Containing Indolines and Tetrahydroquinolines

James. C. Anderson*, Adam Noble and Derek A. Tocher

J. Org. Chem. 2012, 77, 6703–6727

Reductive Nitro-Mannich Route for the Synthesis of 1,2-Diamine Containing Indolines and Tetrahydroquinolines

NMR Chemical Shifts of Molecules Encapsulated in Single Walled Carbon Nanotubes

Nicholas A. Besley* and Adam Noble

J. Chem. Phys. 2008, 128, 101102 (link)

Time-Dependent Density Functional Theory Study of the X-ray Absorption Spectroscopy of Acetylene, Ethylene and Benzene on Si(100)

Nicholas A. Besley* and Adam Noble

J. Phys. Chem. C 2007, 111, 3333–3340 (link)